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FPGA-based digitizer for BGO-based time-of-flight PET
1Department of Biomedical Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, United States of America.
Physics in Medicine and Biology
|March 20, 2025
Summary
A novel field-programmable gate array (FPGA) digitizer precisely measures scintillation and Cerenkov photons from bismuth germanate (BGO) crystals. This BGO time-of-flight (TOF) digitizer achieves excellent timing resolution, suitable for advanced PET systems.
Area of Science:
- Nuclear Instrumentation
- Medical Physics
- Photon Detection
Background:
- Bismuth germanate (BGO) crystals produce both scintillation and prompt Cerenkov photons upon interaction with 511 keV photons.
- Independent processing of these photon types is crucial for accurate energy and timing measurements in BGO detectors.
Purpose of the Study:
- To develop and validate a novel field-programmable gate array (FPGA)-based time-of-flight (TOF) digitizer for bismuth germanate (BGO) detectors.
- To enable precise, independent measurement of scintillation and prompt Cerenkov photons for enhanced detector performance.
- To assess the digitizer's suitability for multi-channel applications, such as Positron Emission Tomography (PET) systems.
Main Methods:
- Implementation of a noise-resistant binary counter using the time-over-threshold (TOT) method for energy measurement.
- Integration of an embedded dual-side monitoring time-to-digital converter for efficient, low-resource timing acquisition.
- Experimental validation using BGO pixels coupled to silicon photomultipliers, including electrical testing and coincidence measurements.
Main Results:
- The FPGA-based TOF digitizer achieved a coincidence timing resolution (CTR) of 407 ps FWHM.
- Performance was comparable to traditional oscilloscope measurements (403 ps FWHM).
- The design demonstrated low resource utilization, indicating high scalability potential.
Conclusions:
- The developed FPGA-based TOF digitizer effectively processes dual photon types from BGO crystals.
- The digitizer offers high-precision timing and energy measurements with performance comparable to oscilloscopes.
- Its low resource footprint and scalability make it ideal for developing advanced, multi-channel BGO-based PET systems.

