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Related Concept Videos

Infrared (IR) Spectroscopy: Overview01:09

Infrared (IR) Spectroscopy: Overview

1.4K
When electromagnetic radiation passes through a material, atoms or molecules transition from a lower to a higher energy state by absorbing radiation corresponding to the energy difference between the two states. The absorption of infrared (IR) radiation causes transitions between vibrational energy levels in a molecule. Therefore, IR spectroscopy is a useful analytical tool for determining the molecular structure of molecules.
Different compounds display unique properties due to their...
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IR Spectrometers01:25

IR Spectrometers

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There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...
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IR Spectrum01:19

IR Spectrum

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When infrared (IR) radiation passes through a molecule, the bonds stretch or bend by absorbing the radiation. This absorption creates the molecule's absorption spectrum, which is the plot of its percentage transmittance versus wavenumber.
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
877
IR Frequency Region: Fingerprint Region01:03

IR Frequency Region: Fingerprint Region

679
IR spectra are divided into two main regions: the diagnostic region and the fingerprint region. The diagnostic region of the spectrum lies above 1500 cm−1. The absorptions resulting from single-bond vibrations of the N–H, C–H, and O–H stretch at higher wavenumbers and appear on the left side of the spectrum. The stretching absorptions of the C≡C and C≡N occur between 2100–2300 cm−1. In contrast, those arising from stretching absorptions of the...
679
IR Spectrum Peak Intensity: Amount of IR-Active Bonds00:55

IR Spectrum Peak Intensity: Amount of IR-Active Bonds

576
When infrared radiation is passed through a molecule, absorption occurs if the molecule's vibration leads to a substantial change in its bond dipole moment. Transitions between vibrational energy levels, typically corresponding to infrared frequencies (4000–400 cm−1), allow absorption if the vibration significantly alters the dipole moment, making the molecule infrared active. The molecular bonds have different stretching and bending vibrations, resulting in various peaks with...
576
IR Spectrum Peak Intensity: Dipole Moment01:20

IR Spectrum Peak Intensity: Dipole Moment

617
The dipole moment of a bond is the product of the partial charge on either atom and the distance between them. Dipole moments influence the efficiency of IR absorption and the peak intensity. When a bond with a dipole moment is placed in an electric field, the direction of the field determines if the bond is compressed or stretched. Electromagnetic radiation consists of an electric field component that rapidly reverses direction. It follows that polar bonds are alternately stretched and...
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High-definition Fourier Transform Infrared FT-IR Spectroscopic Imaging of Human Tissue Sections towards Improving Pathology
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Mid-Infrared Energy Deposition Spectroscopy.

Jiaze Yin1,2, Christian Pfluegl3, Chu C Teng3

  • 1Boston University, Department of Electrical and Computer Engineering, Boston, Massachusetts 02215, USA.

Physical Review Letters
|March 25, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces mid-infrared energy deposition (MIRED) spectroscopy, achieving microsecond temporal and submicron spatial resolution. This novel photothermal spectroscopy method overcomes thermal diffusion limits for faster spectral acquisition.

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Area of Science:

  • Spectroscopy
  • Physical Chemistry
  • Materials Science

Background:

  • Photothermal spectroscopy's speed is typically limited by thermal diffusion.
  • Faster spectral acquisition is crucial for advanced material analysis and dynamic processes.

Purpose of the Study:

  • To develop a photothermal spectroscopy technique with enhanced temporal and spatial resolution.
  • To overcome the fundamental limitations imposed by thermal diffusion in spectral acquisition.

Main Methods:

  • Demonstration of mid-infrared energy deposition (MIRED) spectroscopy.
  • Optical probing of photothermal processes with rapidly tuned infrared pulses from a quantum cascade laser array.
  • Utilizing Newton's law of heating and cooling to determine instantaneous absorption from energy deposition measurements.

Main Results:

  • Achieved microsecond-scale temporal resolution and submicron spatial resolution.
  • Demonstrated that energy deposition, as the first derivative of temperature rise, provides instantaneous absorption.
  • Shifted the spectral encoding limit to the picosecond-scale vibrational relaxation time.

Conclusions:

  • MIRED spectroscopy significantly increases detection bandwidth.
  • The method retains the inherent sensitivity and resolution advantages of photothermal detection.
  • This technique offers a new paradigm for high-speed, high-resolution spectroscopic analysis.