Related Experiment Video
Updated: May 20, 2025
14:54
Biobanking of Human Aqueous and Vitreous Liquid Biopsies for Molecular Analyses
Published on: September 11, 2023
2.2K
Intraocular Tumor Biopsy
Khushboo Chauhan1, Arun Singh2, Vishal Raval1,3
1Ophthalmologist, Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, India.
Seminars in Ophthalmology
|March 25, 2025
Summary
Intraocular biopsy is vital for diagnosing eye conditions when other methods fail. Advancements improve its safety and effectiveness for better patient outcomes.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Intraocular biopsy obtains tissue samples to diagnose eye lesions like tumors, infections, and inflammatory conditions.
- It is essential when clinical and imaging findings are inconclusive.
Purpose of the Study:
- To review the literature on intraocular biopsy techniques, applications, and advancements.
- To highlight its role in diagnosis and treatment planning for intraocular lesions.
Main Methods:
- Retrospective literature review up to July 2024.
- Inclusion of reviews, original articles, case reports, and case series.
Main Results:
- Various techniques exist, including fine-needle aspiration biopsy (FNAB), vitreous biopsy, and chorioretinal biopsy.
- Despite challenges (small sample size, complications), it guides management and treatment.
- Advancements in molecular pathology and imaging enhance yield and safety.
- Prognostic biopsy for uveal melanoma is standard care in ocular oncology.
Conclusions:
- Intraocular biopsy is crucial for treatment decisions and improving patient outcomes.
- Technological progress enhances its efficacy and safety in ophthalmic practice.
