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Updated: May 20, 2025
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A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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How We Approach Contraception for Adolescents and Young Adults With Sickle Cell Disease
Maayan Leroy-Melamed1,2, Patrick McGann1,3, Layla Van Doren4
1Brown University Health, Comprehensive Sickle Cell Center, Providence, Rhode Island, USA.
Pediatric Blood & Cancer
|March 26, 2025
Summary
Individuals with sickle cell disease (SCD) are living longer, increasing focus on sexual and reproductive health (SRH). Contraception counseling for SCD requires a patient-centered approach due to unique health complexities.
Area of Science:
- Hematology
- Reproductive Health
- Patient Care
Background:
- Effective disease-modifying therapies are improving longevity for individuals with sickle cell disease (SCD).
- Increased lifespan has heightened the importance of sexual and reproductive health (SRH) discussions in SCD care.
- SRH remains an underemphasized component of comprehensive SCD management.
Observation:
- Contraception choices for individuals with SCD present unique challenges.
- These challenges are linked to SCD-related pain and thrombophilia.
- A case-based approach illustrates complex contraception considerations.
Findings:
- A multidisciplinary team is essential for effective SRH care in SCD.
- Holistic and patient-centered strategies are crucial for contraception counseling.
- Addressing pain and thrombophilia is key when selecting contraceptive methods.
Implications:
- Integrating SRH into routine SCD care is vital.
- Specialized contraception guidance can improve health outcomes for individuals with SCD.
- Further research into optimal SRH strategies for SCD patients is warranted.
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