Association Between Ménière's Disease and Thyroid Disease: A Systematic Review and Meta-Analysis

The relationship between thyroid disease and Ménière's disease (MD) remains controversial. This article aims to explore the association between thyroid disease and MD and provide new evidence for the prevention and treatment of MD and its complications.

A systematic review and meta-analysis.

PubMed, EMBASE, Web of Science and Cochrane Library were searched until July 08, 2024. Based on the eligibility criteria, the literature was screened, the data were extracted, and the study quality was evaluated. The prevalence and/or incidence of MD in thyroid disease and the prevalence and/or incidence of thyroid disease in MD were explored. The pooled proportion with 95% confidence interval (CI) was calculated using a random-effects model.

Eighteen eligible studies were finally enrolled. A total of 14 studies mentioned the prevalence of thyroid disease in MD, with a pooled prevalence rate of 8%. Two studies reported the prevalence of MD in thyroid patients, with a pooled prevalence rate of 22%. Four studies explored the incidence of thyroid disease in MD, with a combined incidence rate of 23%. Thyroid hormone treatment not only improved hypothyroidism symptoms but also MD.

There is a significant association between thyroid disease and MD. Symptoms of hypothyroidism and MD can be improved after thyroid hormone treatment. The available evidence is limited, and more prospective and high-quality studies are required for validation.