Related Experiment Video
Updated: May 20, 2025
Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Targeted and regional biopsy in prostate cancer: first real-world data
Thibaut Long-Depaquit1,2, Renaud Corral3, Alessandro Uleri3
1Department of Urology, HIA Sainte-Anne, Toulon, France. Thibaut.long2@gmail.com.
Introduction:
MRI-targeted biopsies enhance prostate cancer (PCa) diagnostics, but systematic distant biopsies increase overdiagnosis and overtreatment. Regional biopsies may optimize diagnostic efficiency.
Methods:
This prospective single-center study included biopsy-naïve patients undergoing transperineal MRI-guided biopsies with cognitive fusion and regional sampling.
Results:
Among 50 patients, 66% had clinically significant PCa, 16% insignificant PCa, and 18% no cancer. No re-biopsies were needed for non-cancerous cases. Of 12 patients undergoing nerve-sparing radical prostatectomy, 25% had a bilateral disease, with two positive margins.
Conclusion:
This novel biopsy template may help reduce unnecessary sampling and associated risks. Larger comparative studies are needed to confirm these findings.
