Related Experiment Video
Updated: Jul 11, 2026

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
Published on: July 31, 2014
Recurrence Rate in Children With Arterial Ischemic Stroke: A Systematic Review
Jacob Bastrup1, Thomas Truelsen1,2, Julie Brix Bindslev1,3
1Department of Neurology, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.
Aim:
We conducted a systematic review to examine the recurrence rate in children with arterial ischemic stroke, including the recurrence rate according to stroke aetiology.
Methods:
This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. PubMed and Embase were searched for English-language cohort studies published between 1 January 2000 and 19 January 2023, reporting the recurrence rate in children with AIS. Identified studies were screened by two researchers on title/abstract level and full-text level. The risk of bias was assessed using the modified Critical Appraisal Skills Programme checklist.
Results:
The search yielded 28 studies, including 5546 children and 684 neonates. The studies were from 14 different countries with two international cohorts. Reported recurrence rates ranged from 0.0% to 1.9% for neonatal cohorts and 1.1% to 51.9% for childhood cohorts. The median recurrence rate was 10.6% for childhood AIS cohorts. Arteriopathies represented a high-risk aetiology associated with recurrence rates of 0.0%-52.2% with a median recurrence rate of 21.8%.
Conclusion:
These findings indicated that subgroups of patients possess a higher recurrence risk than others. Differences between studies highlighted the need for systematic approaches to future research on predictors of recurrent AIS.
More Related Videos
09:11Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
Published on: February 23, 2016
07:56Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Stroke: Introduction and Types
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology