Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inner ear immunology.

G Mogi, H Kawauchi, M Suzuki

    American Journal of Otolaryngology
    |May 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    The inner ear immune system is separate from the cerebrospinal fluid system. While dilated blood vessels slightly increased antibody transfer to the perilymph, local antibody production was not observed.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    European Position Paper on Rhinosinusitis and Nasal Polyps 2020.

    Rhinology·2020
    Same author

    Severe Chronic Upper Airway Disease (SCUAD) in children. Definition issues and requirements.

    International journal of pediatric otorhinolaryngology·2015
    Same author

    Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study.

    Allergy·2015
    Same author

    Japanese traditional medicine, Senn-kinn-naidaku-sann up-regulates Toll-like receptor 4 and reduces murine allergic rhinitis.

    Rhinology·2014
    Same author

    SCUAD and chronic rhinosinusitis. Reinforcing hypothesis driven research in difficult cases.

    Rhinology·2014
    Same author

    A radioimmunoassay for N-terminal peptide of chum salmon proopiocortin.

    Fish physiology and biochemistry·2013
    Same journal

    Multifunctional xylitol-HA hydrogel for chronic rhinosinusitis management.

    American journal of otolaryngology·2026
    Same journal

    Outcomes of pediatric tracheostomy with a standardized surgical technique: A retrospective single-center analysis.

    American journal of otolaryngology·2026
    Same journal

    Comment on "Modified ultrasound-guided polidocanol sclerotherapy is an effective treatment for thyroid cystic-solid nodules: A single-center retrospective study".

    American journal of otolaryngology·2026
    Same journal

    Managing post-extubation dysphagia after prolonged intubation: A systematic review of Speech-Language Pathology (SLP) approaches.

    American journal of otolaryngology·2026
    Same journal

    Rethinking indications for prophylactic central neck dissection in papillary thyroid microcarcinoma: A real-world retrospective study.

    American journal of otolaryngology·2026
    Same journal

    Letter to the editor regarding "Development of a novel self-assessment tool following endoscopic sinus surgery in the management of chronic rhinosinusitis".

    American journal of otolaryngology·2026
    See all related articles

    Area of Science:

    • Immunology
    • Otolaryngology
    • Neuroscience

    Background:

    • The immune system of the inner ear's perilymphatic space was previously hypothesized to be distinct from the cerebrospinal fluid's immune system.
    • Understanding immune system interactions within the inner ear is crucial for diagnosing and treating auditory and vestibular disorders.

    Purpose of the Study:

    • To investigate the impact of cochlear blood vessel dilation on serum antibody transfer to the perilymph.
    • To determine if antibodies can be locally produced within the perilymphatic space of the inner ear.

    Main Methods:

    • Chinchillas were used to study the effect of dilated blood vessels surrounding the cochlea on serum antibody transfer to the perilymph.
    • Antigen was introduced into the inner ear via the facial nerve canal to assess local antibody production in the perilymphatic space.

    Related Experiment Videos

    Main Results:

    • Dilation of blood vessels around the cochlea enhanced the transfer of serum antibodies into the perilymph, although this effect was limited.
    • Introduction of antigen into the inner ear did not result in local antibody production within the perilymphatic space.

    Conclusions:

    • The findings support the independence of the inner ear's perilymphatic immune system from the cerebrospinal fluid.
    • Evidence suggests that local antibody production does not occur within the perilymphatic space of the inner ear.