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Related Concept Videos

Introduction to Lymphatic and Immune System01:22

Introduction to Lymphatic and Immune System

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Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
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Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

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The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
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Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

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Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
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Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

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Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
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Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Related Experiment Video

Updated: May 20, 2025

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

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[The lymphatic system-an interdisciplinary challenge].

Moritz Wildgruber1, Wilhelm Flatz2, Matthias P Fabritius2

  • 1Klinik und Poliklinik für Radiologie, LMU Klinikum, Marchioninistraße 15, 81377, München, Deutschland. moritz.wildgruber@med.uni-muenchen.de.

Radiologie (Heidelberg, Germany)
|March 27, 2025
PubMed
Summary
This summary is machine-generated.

Radiology plays a key role in diagnosing and treating lymphatic system diseases. New diagnostic and therapeutic techniques, including MR lymphography and transnodal lymphangiography, offer improved patient care pathways.

Keywords:
ChylascitesChylothoraxEmbolizationLymphangiographyLymphatic malformation

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Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
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Area of Science:

  • Diagnostic and interventional radiology
  • Lymphatic system diseases
  • Minimally invasive therapies

Context:

  • Lymphatic system diseases present significant diagnostic challenges.
  • Radiology is central to the clinical workflow for these conditions.
  • New diagnostic and therapeutic options are expanding the role of radiology.

Purpose:

  • To provide an overview of the differential diagnostic spectrum of lymphatic diseases.
  • To outline diagnostic procedures and therapeutic options.
  • To present clinical workflows for managing lymphatic system conditions.

Summary:

  • Diseases and injuries of the lymphatic system have a broad differential diagnostic spectrum.
  • Accurate classification using patient history, clinical presentation, and imaging is crucial.
  • Procedures like MR lymphography and transnodal fluoroscopic lymphangiography are key diagnostic tools.
  • Transnodal lymphangiography enables minimally invasive therapies such as recanalization, embolization, or sclerosing techniques.
  • Interdisciplinary care in specialized centers improves outcomes for complex lymphatic diseases.

Impact:

  • Advances in diagnostic lymphangiography and interventional radiology present new challenges.
  • An interdisciplinary approach is essential for managing complex lymphatic system cases.
  • Specialized centers and collaborative care models enhance patient management, similar to oncology pathways.