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Sarcoidosis in India.

S K Gupta, K Mitra, S Chatterjee

    British Journal of Diseases of the Chest
    |July 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Sarcoidosis in India often affects elderly males, showing significant chest abnormalities with few symptoms. While relapses are common, they respond well to steroid treatment.

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    Area of Science:

    • Pulmonology
    • Rheumatology
    • Immunology

    Background:

    • Sarcoidosis presentation in India differs from Western populations.
    • Elderly males are frequently affected, with radiological findings often exceeding clinical signs.

    Purpose of the Study:

    • To compare sarcoidosis characteristics in India with Western and global data.
    • To analyze trends in sarcoidosis detection and clinical presentation in India.

    Main Methods:

    • Comparative analysis of a series of 90 Indian sarcoidosis cases (1957-1982) against Western and World data.
    • Review of detection rates in specialized Indian centers over several decades.

    Main Results:

    • Indian sarcoidosis commonly affects elderly males, with frequent clubbing but rare erythema nodosum, generalized lymphadenopathy, eye changes, and bone cysts.

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  • Spontaneous resolution is rare; relapses are frequent but responsive to short steroid courses.
  • Sarcoidosis detection has increased in India, with varying rates between centers.

    • Conclusions:

    • Sarcoidosis in India exhibits distinct epidemiological and clinical features compared to other regions.
    • Increased detection may reflect rising incidence or improved awareness.
    • Management often involves steroids for relapsing disease.