Progress and Priorities to End the HIV Epidemic by 2030: Combined Lessons From 120 US Implementation Research...

Area of Science:

• Implementation Science
• Public Health
• HIV Prevention Research

Background:

• The US national Ending the HIV Epidemic (EHE) plan aims to reduce new HIV infections by 90% by 2030.
• Five years into the EHE plan, a synthesis of implementation research is crucial for achieving its goals.

Purpose of the Study:

• To synthesize lessons learned from numerous NIH-funded implementation research projects under the EHE initiative.
• To identify generalizable implementation science findings across diverse sites, studies, and contexts.

Main Methods:

• Analysis of 24 collaborative papers summarizing shared HIV implementation knowledge.
• Inclusion of work from 111 EHE supplement projects, 7 R01s, the Implementation Science Coordination Initiative (ISCI), and 9 regional consultation hubs (RCHs).
• Focus on research conducted in 40 EHE priority jurisdictions.

Main Results:

• Identified 4 overarching themes: infrastructure for HIV implementation research, methods for community-specific research, implementation strategies for HIV interventions, and training for the HIV workforce.
• Highlighted the importance of robust research infrastructure, sustainable workforce investments, and strong partnerships.

Conclusions:

• The synthesis provides a clear pathway for the next phase of the EHE plan.
• Continued focus on research infrastructure, workforce sustainability, and bridging local innovation with systemic change is essential for future success in HIV prevention.