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Updated: May 16, 2025

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
Published on: February 27, 2015
The soft-membrane surface forces apparatus
Ilyes Jalisse1, Aditya Jha2, Lionel Buisson1
1Univ. Bordeaux, CNRS, CRPP, UMR 5031, F-33600 Pessac, France.
Abstract:
Compliant walls are widespread in biological and engineering systems. Because of their singular nature, adapted tools are required to accurately study their rheological properties and the consequences of the latter within a given mechanical setting. Because of their slender nature, membranes can be considered as prototypical examples of highly compliant boundaries. In this study, we describe a modified surface forces apparatus developed to measure the forces acting on a compliant membrane by measuring its deformation field. We discuss how such a device can be used to characterize the rheology of suspended membranes and accurately measure the electrostatic interactions between a polarized membrane and a spherical electrode, without the need of an external measurement spring.

