Hydrogel adhesives for tissue recovery

Area of Science:

• Biomaterials Science
• Tissue Engineering
• Adhesive Technology

Background:

• Hydrogel adhesives (HAs) show significant promise for tissue therapy.
• They offer potential applications as suture replacements, for drug delivery, and hemostatic sealing.

Purpose of the Study:

• To systematically review common designs and recent advancements in hydrogel adhesives.
• To highlight strategies for achieving robust wet adhesion and balancing adhesion properties.

Main Methods:

• Systematic literature review of hydrogel adhesive methodologies.
• Analysis of strategies for interfacial water management and adhesion control.
• Discussion of gelation strategies and raw materials.

Main Results:

• Hydrogel adhesives demonstrate excellent properties for biological tissue applications.
• Effective strategies exist for creating strong wet adhesion and tunable non-adhesion.
• Various gelation methods and raw materials are available for HA development.

Conclusions:

• Hydrogel adhesives are versatile tools for improving tissue therapy management.
• Further research into novel HA designs and applications is warranted.
• This review provides insights for developing practical hydrogel adhesives for diverse medical needs.