Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

27.2K
Overview
27.2K
Cross-reactivity00:42

Cross-reactivity

30.9K
Overview
30.9K
Hypersensitivities01:30

Hypersensitivities

426
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
426
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

402
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
402
Allergic Drug Reactions01:27

Allergic Drug Reactions

799
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
799
Antibody Structure01:10

Antibody Structure

58.6K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
58.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing-Recommendations on Best Practice (Update 2026).

Contact dermatitis·2026
Same author

Methylchloroisothiazolinone and Methylisothiazolinone 10 Years After Regulation: A Case Story of Liquid Soaps and Shampoos.

Contact dermatitis·2026
Same author

Mapping of Former Strategies and Future Needs for Regulatory Prevention of Skin Sensitization: Cosmetic Products.

Contact dermatitis·2026
Same author

Gold and Nickel Release From Gold-Plated Earrings Under Cysteine-Modified Artificial Sweat Conditions.

Contact dermatitis·2026
Same author

Chromium and Cobalt in Used Leather Items: A Danish Market Survey.

Contact dermatitis·2026
Same author

The Prevalence of Contact Allergy to Formaldehyde and Formaldehyde Releasers: A Systematic Review and Meta-Analysis.

Contact dermatitis·2026
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Related Experiment Video

Updated: May 16, 2025

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10
10:42

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10

Published on: November 19, 2016

7.5K

[Contact allergens].

Kristian Fredløv Mose1, Jeanne Duus Johansen2, Anne Birgitte Simonsen2

  • 1Hudafdeling og Allergicentret, Odense Universitetshospital.

Ugeskrift for Laeger
|April 2, 2025
PubMed
Summary
This summary is machine-generated.

New chemical substances in industry lead to novel contact allergens. This review updates on emerging allergens like rubber accelerators, acrylates, preservatives, and antioxidants, plus new uses for known ones.

More Related Videos

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens
09:09

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens

Published on: February 24, 2021

2.9K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

3.1K

Related Experiment Videos

Last Updated: May 16, 2025

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10
10:42

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10

Published on: November 19, 2016

7.5K
Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens
09:09

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens

Published on: February 24, 2021

2.9K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

3.1K

Area of Science:

  • Dermatology
  • Toxicology
  • Occupational Health

Background:

  • Over 5,200 contact allergens are documented.
  • Industrial use of new chemicals and products constantly introduces potential allergens.
  • Identification of new contact allergens is an ongoing challenge.

Purpose of the Study:

  • To provide an updated overview of newly identified contact allergens.
  • To highlight emerging allergens in specific categories like rubber accelerators, acrylates, preservatives, and antioxidants.
  • To discuss novel applications of previously known allergens.

Main Methods:

  • Literature review of recent scientific publications.
  • Analysis of industry reports and regulatory updates.
  • Synthesis of information on emerging chemical substances and their allergenic potential.

Main Results:

  • Several new contact allergens have been identified in recent years.
  • Specific chemical classes, including rubber accelerators, acrylates, preservatives, and antioxidants, show emerging allergenic concerns.
  • Known allergens are increasingly found in new product types and applications.

Conclusions:

  • The continuous introduction of new chemicals necessitates ongoing surveillance for contact allergens.
  • Awareness of emerging allergens is crucial for occupational health and consumer safety.
  • Further research is needed to fully characterize the risks associated with new and re-emerging contact allergens.