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Artificial intelligence in bacterial diagnostics and antimicrobial susceptibility testing: Current advances and
Seungmin Lee1, Jeong Soo Park2, Ji Hye Hong1
1KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea; School of Biomedical Engineering, Korea University, 145 Anam-ro, Seongbuk, Seoul, 02841, Republic of Korea.
Artificial intelligence (AI) is revolutionizing bacterial diagnostics and antimicrobial susceptibility testing (AST). AI offers faster, more accurate, and scalable solutions, especially for resource-limited settings.
Area of Science:
- Microbiology
- Computational Biology
- Medical Diagnostics
Background:
- Traditional bacterial diagnostics and antimicrobial susceptibility testing (AST) face limitations in speed, accuracy, and scalability.
- Current methods often require specialized infrastructure and expertise, hindering accessibility, particularly in resource-limited settings.
- Artificial intelligence (AI) presents a promising avenue to overcome these challenges.
Purpose of the Study:
- To review the transformative role of AI in bacterial detection and AST.
- To explore various machine learning and deep learning models applied in AI-driven diagnostics.
- To highlight AI's potential in resource-limited settings and future advancements.
Main Methods:
- Leveraging machine learning models like Random Forest, Support Vector Machines (SVM), and deep learning architectures (CNNs, transformers).
- Examining AI applications across diverse detection techniques including microscopy, spectroscopy (Raman, SERS), mass spectrometry, and sensor-based methods.
- Analyzing AI's role in automating data analysis and enabling real-time results.
Main Results:
- AI significantly enhances the speed, accuracy, and scalability of bacterial diagnostics and AST.
- AI-based approaches offer cost-effective, portable solutions suitable for resource-limited environments.
- AI facilitates remote diagnostics via smartphone integration and telemedicine.
Conclusions:
- AI is revolutionizing bacterial diagnostics and AST, improving efficiency and accessibility.
- AI integration minimizes human error and optimizes healthcare outcomes.
- Future directions point towards further advancements in AI-driven bacterial detection and susceptibility testing.
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