![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
18 F-FDG PET/CT Findings in a Case of Plasmablastic Myeloma: A Rare Entity
Nivedita Kundu1, Aparna Mahalik, Dikhra Khan
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Plasmablastic myeloma (PBM) is an extremely rare variant of multiple myeloma, having morphologic, clinical, and radiologic overlap with plasmablastic lymphoma (PBL). Thus, distinguishing both becomes vital due to different treatment strategies. Due to limited literature on imaging findings in this rare entity, here we present a unique case of PBM developing in the setting of chronic light chain myeloma, with extensive extramedullary involvement and severe osteopenia, in addition to pleural deposits, pleural effusion, and perinephric fascial deposit. Thus, 18F-FDG PET/CT can be utilized as an important tool in distinguishing PBM and PBL on imaging, assessing disease extent, and identifying critical lesions requiring immediate intervention.
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