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Updated: May 15, 2025

Author Spotlight: Visualizing Single-Stranded DNA During DNA Repair for Therapeutic Insights
Published on: December 22, 2023
The 12th 3R + 3C International Symposium: A Meeting for Research Into DNA Replication, Repair, and Recombination, as
Tsutomu Katayama1, Masatoshi Fujita1, Tatsuro S Takahashi2
1Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Abstract:
The 12th 3R + 3C international symposium focused on cutting-edge research into the molecular mechanisms and regulatory systems of DNA replication, repair, and recombination (3R) as well as those of chromatin dynamics, chromosome architecture, and the cell cycle (3C). It also covered pioneering research into how these processes control cell growth, cell homeostasis, differentiation, development, and aging, in addition to how they contribute to diseases such as cancer, chromosomal abnormalities, and evolution of organisms. In terms of methodology, the symposium highlighted new trends in single-molecule/single-cell analysis, cryo-electron microscopy analysis, kinetic analysis of higher-order protein complexes, informatic analysis of genome dynamics, and new mathematical and theoretical analyses. Held in Fukuoka City center from November 18 to 22, 2024, this symposium attracted about 250 participants, including approximately 150 from Japan and nearly 100 from overseas. To foster mutual understanding and exchange between different fields, all the oral presentations took place in a single conference hall throughout the symposium. This format facilitated active and in-depth discussions among participants, including young researchers, graduate students, and postdoctoral fellows.
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