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Unilateral Iris Transillumination Resembling BAIT Phenotype Following Contralateral Vitrectomy
Olivier Lambrechts1, Luc Van Os1
1Ophthalmology, University Hospital Antwerp, Edegem, Belgium.
Case Reports in Ophthalmological Medicine
|April 14, 2025
Summary
This case study reports the first unilateral presentation of acute iris transillumination (BAIT) after contralateral vitrectomy. It suggests prior treatments may offer protection against developing BAIT syndrome.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Uveitis
Background:
- Acute iris transillumination (BAIT) syndrome is a rare condition.
- Vitrectomy is a common surgical procedure for retinal diseases.
- Postoperative endophthalmitis is a serious complication of ocular surgery.
Observation:
- A 70-year-old female developed unilateral BAIT in her left eye after undergoing vitrectomy and treatment for endophthalmitis in her right eye.
- The right eye, which had the initial surgery and endophthalmitis, did not develop BAIT.
- The patient received various treatments including topical corticosteroids, antibiotics, and intravitreal vancomycin.
Findings:
- This is the first reported case of a unilateral BAIT phenotype following contralateral vitrectomy.
- The affected eye showed patchy iris transillumination.
- The contralateral eye remained unaffected.
Implications:
- Previous vitrectomy may confer a protective effect against developing BAIT.
- Specific medications like vancomycin, topical corticosteroids, or chloramphenicol might play a role in preventing BAIT.
- Further research is needed to understand the mechanisms behind unilateral BAIT and potential protective factors.

