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Relapsing-remitting multiple sclerosis as a potential consequence of thalidomide treatment: A case report
Rodolfo Francisco Marques1, Denison Alves Pedrosa2, Natalia Talim1
1CIEM MS Research Center, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil.
Thalidomide may cause central nervous system (CNS) demyelination, leading to conditions like clinically isolated syndrome and multiple sclerosis. This highlights the need for caution when prescribing thalidomide, especially in at-risk patients.
Area of Science:
- Neuroimmunology
- Pharmacology
Background:
- Thalidomide is used for conditions like prurigo nodularis.
- Tumor necrosis factor-alpha (TNF-α) inhibitors are known to cause CNS lesions.
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