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Updated: May 11, 2025

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
Workup, Indications, and Guiding Principles of Selection for Pulmonary Metastasectomy
Kelly Fairbairn1, Hari B Keshava1
1Division of Thoracic Surgery, Department of Surgery, University of California, 3800 West Chapman Avenue, Suite 6200, Orange, CA 92868, USA.
Abstract:
Pulmonary metastasectomy is a potentially curative intervention for many different and distinct primary malignancies. It is safe in a diverse patient population. A short disease-free interval, multiple metastases, large metastases, and incomplete resection are all poor prognostic indicators for survival. Patients should be approached as any lung resection patient would, including a full history and physical, and a thorough review of their imaging, labs, medications, previous surgeries, and pulmonary function tests. All patients should be discussed at a multidisciplinary tumor board, and a formal and united plan with input from all specialties should be developed before offering surgical intervention.
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