[Organic psychosyndrome with and without lithium therapy]

Area of Science:

• Neuroscience
• Psychiatry

Background:

• Lithium salts are a common treatment for mood disorders.
• The long-term effects of lithium on cognitive function require further investigation.

Purpose of the Study:

• To evaluate the impact of two-year lithium salt treatment on cognitive functions and overall well-being.
• To compare cognitive and functional outcomes between lithium-treated patients and a control group.

Main Methods:

• A longitudinal study design was employed.
• Patients received lithium salt treatment for two years.
• Cognitive assessments and functional evaluations were conducted.

Main Results:

• No cases of organic brain syndrome were observed in the lithium-treated group.
• Significant improvements in thinking, concentration, short-term memory, attention, and conception were noted in lithium-treated patients.
• Lithium-treated patients demonstrated increased self-confidence, flexibility, and problem-solving skills compared to the control group, who showed mood dependency and no efficiency improvement.

Conclusions:

• Two-year lithium salt treatment is safe and does not induce organic brain syndrome.
• Lithium therapy positively impacts cognitive functions and enhances psychological well-being and daily functioning.
• Lithium treatment offers a significant advantage over standard care for improving patient efficiency and resilience.