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Updated: May 10, 2026
Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Predictive factors for postoperative outcome after endolymphatic sac surgery. Part 2: Quality of life
A Derieppe1, K Bourget-Aguilar1, P Bordure1
1Service d'ORL et Chirurgie Cervico-Faciale, CHU de Nantes Hôtel-Dieu, 1, place Alexis-Ricordeau, 44000 Nantes, France.
Objective:
To evaluate improvement in quality of life (QoL) 2years after endolymphatic sac surgery (ESS) in patients with Ménière's disease (MD), and preoperative factors for QoL.
Materials And Methods:
A retrospective single-center study included patients who underwent ESS between 2015 and 2022, with unilateral MD according to the criteria of the American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) as revised in 2015, and resistant to first-line medical treatment. The main study endpoint was quality of life, measured on the MDOQ-R questionnaire.
Results:
Thirty-eight patients were included. Mean improvement in MDOQ-R score was 31.1±24.6 points [range: -29 to 79], and was significant (P<0.001). No predictive factors were identified.
Conclusion:
ESS provided significant and lasting improvement in quality of life. However, it was not possible to identify preoperative predictive factors for a "typical" patient profile with the highest likelihood of favorable outcome.
