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Updated: May 11, 2025

A Novel Method: Super-selective Adrenal Venous Sampling
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Update on Adrenocortical Carcinoma
Zahra Sarrafan-Chaharsoughi1, Pouria Yazdian Anari2, Ashkan A Malayeri3
1Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Abstract:
Adrenocortical carcinoma (ACC) is an uncommon and highly aggressive form of cancer that originates from the adrenal glands. It displays a dual age distribution pattern, with a higher occurrence during early childhood around the average age of 3.2 years, and a second peak in the fourth and fifth decades of adulthood. The diagnosis of ACC requires a multifaceted approach, with accurate risk assessment being crucial for effective treatment planning. This review article offers a comprehensive overview of ACC, encompassing its epidemiology, clinical presentation, diagnosis, prognostic factors, and treatment methodologies.
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