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Skin Cancer

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Related Experiment Video

Updated: May 11, 2025

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

New Dermoscopy Pattern in Nevus-Associated Melanomas.

Nelson Lobos-Guede^1,2, Dan Hartmann², Valentina Darlic³

¹Melanoma Unit, Dermatology Department, Hospital Clínic de Barcelona, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.

Pigment Cell & Melanoma Research

|April 19, 2025

Summary

This summary is machine-generated.

Nevus-associated melanomas (NAMs) can be challenging to diagnose. This study highlights a rare starburst pattern in NAMs, suggesting early melanoma development within nevi.

Keywords:

dermoscopy melanoma nevus‐associated melanoma reflectance confocal microscopy starburst pattern

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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Area of Science:

Dermatology
Oncology
Pathology

Background:

Melanoma diagnosis is complicated by its origin, either de novo or from pre-existing nevi.
Distinguishing nevus-associated melanomas (NAMs) from benign nevi is clinically and dermoscopically challenging.
Limited research exists on specific dermoscopic features differentiating NAMs from de novo melanomas.

Purpose of the Study:

To report a novel dermoscopic finding in nevus-associated melanomas (NAMs).
To increase awareness of the starburst pattern as a potential indicator of early melanoma within nevi.

Main Methods:

Case series reporting four patients with acquired compound NAMs.
Dermoscopic evaluation of lesions to identify characteristic patterns.
Comparison with existing literature on NAM dermoscopic features.

Main Results:

Four cases of acquired compound NAMs exhibited a central starburst pattern (SP).
This SP finding within NAMs has not been previously reported in medical literature.
The starburst pattern may represent an early melanoma component within a nevus.

Conclusions:

The starburst pattern (SP) in nevi warrants suspicion for early melanoma development.
Clinicians should consider NAMs when encountering nevi with central reticulated pigmentation, especially without trauma history.
Dermoscopy is crucial for identifying subtle melanoma signs in nevus-associated lesions.