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[A CASE OF PELVIC AND INGUINAL LYMPH NODE RECURRENCE OF PENILE CANCER FOR WHICH TIP (PACLITAXEL, IFOSFAMIDE,
Noriaki Noto1, Reona Matsumoto1, Jyun Asano1
1Department of Urology, Fujisaw City Hospital.
Summary
A penile squamous cell carcinoma case study shows successful treatment with penectomy, TIP chemotherapy, and lymphadenectomy, achieving complete remission. This penile cancer management approach prevented recurrence for over two years.
Area of Science:
- Oncology
- Urology
- Surgical Oncology
Background:
- Penile squamous cell carcinoma (PSCC) is a rare malignancy.
- Early-stage PSCC is typically treated with surgery.
- Metastasis to inguinal and iliac lymph nodes significantly impacts prognosis.
Purpose of the Study:
- To report a case of advanced penile squamous cell carcinoma with lymph node metastasis.
- To describe the treatment strategy and outcomes.
- To highlight the effectiveness of combined modality treatment.
Main Methods:
- A 67-year-old male diagnosed with penile squamous cell carcinoma (cT1N0M0) underwent penectomy.
- Due to negative vascular invasion, lymphadenectomy was initially omitted.
- Metastasis detected 4 months post-surgery led to TIP chemotherapy followed by inguinal pelvic lymphadenectomy.
Main Results:
- The patient achieved complete remission after TIP chemotherapy and inguinal pelvic lymphadenectomy.
- No recurrence was observed 2 years and 5 months post-lymphadenectomy.
- The treatment strategy proved effective in managing metastatic penile cancer.
Conclusions:
- Metastatic penile squamous cell carcinoma can be effectively treated with a multimodal approach.
- Delayed lymphadenectomy combined with chemotherapy can lead to durable remission.
- This case underscores the importance of vigilant surveillance and tailored treatment in PSCC management.
