Resolution of Pediatric Mandibular Langerhans Cell Histiocytosis Post-Biopsy

Langerhans cell histiocytosis (LCH) is a rare disease marked by the proliferation of Langerhans cells and the destruction of tissue. LCH can be limited to the oral cavity where it can present with gingival bleeding, swelling, tooth mobility and bone loss. This case report describes a 13-year-old male with LCH who presented with a one-month history of painful jaw swelling. Clinical examination revealed a firm, ulcerated mass adjacent to the mandibular right second premolar. Biopsy and subsequent histopatho- logic examination confirmed LCH. The lesion resolved spontaneously post-biopsy and the patient remains disease-free. Recognizing oral manifestations of LCH in dental practice is crucial for prompt diagnosis, appropriate multidisciplinary management and improving the survival rates and future quality of life for children with LCH.