Vertebral Artery Microcalcification Detected by 18 F-NaF PET/CT
Shiv Patil1,2, Nirmal Patel1,2, Eric Teichner1,2
1Department of Radiology, University of Pennsylvania.
Clinical Nuclear Medicine
|April 25, 2025
Summary
18F-NaF PET/CT imaging detected molecular microcalcification in a patient
Area of Science:
- Vascular Biology
- Radiochemistry
- Neurology
Background:
- Intracranial atherosclerosis is a major cause of stroke and cognitive impairment.
- Detecting active microcalcifications in atherosclerotic plaques is challenging with conventional imaging.
- 18F-NaF PET/CT shows promise for visualizing vascular microcalcification.
Purpose of the Study:
- To report the incidental finding of molecular microcalcification in the vertebral artery using 18F-NaF PET/CT.
- To highlight the potential of 18F-NaF PET/CT in identifying active vascular calcification.
Main Methods:
- A 64-year-old male patient with intracranial atherosclerosis risk factors underwent 18F-NaF PET/CT.
- The imaging focused on detecting vascular microcalcification.
Main Results:
- Incidental molecular microcalcification was observed in the left vertebral artery.
- This finding was visualized using 18F-NaF PET/CT.
Conclusions:
- 18F-NaF PET/CT can detect molecular microcalcification in intracranial arteries.
- This technique may offer new insights into the progression of intracranial atherosclerosis.
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