Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of the Lymphatic System01:15

Development of the Lymphatic System

2.9K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.9K
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

924
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
924

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Strategy for Intractable Inguinal Lymphorrhea Using Combined Indocyanine Green Imaging and Negative Pressure Wound Therapy.

Plastic and reconstructive surgery. Global open·2026
Same author

Reconstruction of extensive gluteal defect following excision of hidradenitis suppurativa using a combined lumbar artery perforator and split superior gluteus maximus musculocutaneous flap: A case report.

JPRAS open·2026
Same author

Severity of deformational plagiocephaly: Role of Wormian and Inca bones.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

Pediatric Digital Artery Pseudoaneurysm From Repetitive Compression While Gripping Toys.

Plastic and reconstructive surgery. Global open·2026
Same author

Pilot Study: Postoperative Evaluation of Upper Extremity Lymphedema Using a Cutometer: A Single-center Prospective Observational Study.

Plastic and reconstructive surgery. Global open·2026
Same author

Dynamic augmentation of lip levator function via depressor anguli oris transfer for post-facial paralysis synkinesis.

JPRAS open·2026

Related Experiment Video

Updated: May 5, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

16.0K

Visualising lymphatic flow dynamics during complex physical therapy: A photoacoustic imaging study.

Yushi Suzuki1, Hiroki Kajita1, Anna Oh1

  • 1Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.

JPRAS Open
|April 28, 2025
PubMed
Summary

Photoacoustic imaging (PAI) visualizes lymphatic flow during complex physical therapy (CPT). This novel approach reveals that combined compression and exercise synergistically enhance lymphatic pumping, offering insights into lymphedema treatment.

Keywords:
Complex physical therapyLymphatic flowLymphedemaPhotoacoustic imaging

More Related Videos

Photoacoustic Cystography
09:49

Photoacoustic Cystography

Published on: June 11, 2013

13.2K
Ovarian Cancer Detection Using Photoacoustic Flow Cytometry
09:18

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Published on: January 17, 2020

5.9K

Related Experiment Videos

Last Updated: May 5, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

16.0K
Photoacoustic Cystography
09:49

Photoacoustic Cystography

Published on: June 11, 2013

13.2K
Ovarian Cancer Detection Using Photoacoustic Flow Cytometry
09:18

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Published on: January 17, 2020

5.9K

Area of Science:

  • Biomedical imaging
  • Vascular biology
  • Lymphedema research

Background:

  • Complex physical therapy (CPT), combining compression and exercise, is crucial for lymphedema management.
  • Visualizing lymphatic vessels in vivo is challenging due to their small size and transparency.
  • Current methods lack the detail for real-time lymphatic flow assessment during therapy.

Purpose of the Study:

  • Introduce photoacoustic imaging (PAI) as a novel method for visualizing lymphatic flow dynamics.
  • Evaluate the efficacy of PAI in assessing lymphatic function under CPT conditions.
  • Explore the synergistic effects of compression and exercise on lymphatic flow.

Main Methods:

  • Employed photoacoustic lymphangiography with indocyanine green in four healthy subjects.
  • Simulated compression therapy (approx. 20 mmHg) using transparent film dressing.
  • Applied exercise stress to mimic CPT conditions while monitoring lymphatic vessels via PAI.

Main Results:

  • PAI provided detailed visualization of lymphatic and blood vessels.
  • Compression caused superficial vein collapse while lymphatic vessels remained intact.
  • Lymphatic pumping frequency was highest during combined compression and exercise, indicating synergy.

Conclusions:

  • PAI is a promising tool for understanding CPT mechanisms in lymphedema.
  • PAI allows simultaneous assessment of veins and lymphatic vessels, aiding vascular change evaluation.
  • Further research is needed due to the study's small sample size and specific exercise regimen.