Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioreactor Controls-I01:28

Bioreactor Controls-I

94
Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly...
94
Bioreactor Controls-II01:18

Bioreactor Controls-II

76
In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the...
76
Upstream Processing01:27

Upstream Processing

97
Upstream processing represents a critical phase in biomanufacturing, wherein biological systems such as microorganisms, mammalian cells, or insect cells are cultivated to produce therapeutic proteins, vaccines, enzymes, or other biologically derived products. This phase encompasses all steps from the selection and genetic manipulation of the production organism to the cultivation of cells in bioreactors under tightly controlled environmental conditions.Host Selection and Genetic OptimizationThe...
97

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal soft valve enables physical responsiveness for preemptive resilience of soft robots.

Science robotics·2024
Same author

Modeling of Soft Pneumatic Actuators with Different Orientation Angles Using Echo State Networks for Irregular Time Series Data.

Micromachines·2022
Same author

Underwater Soft Robotics: A Review of Bioinspiration in Design, Actuation, Modeling, and Control.

Micromachines·2022
Same author

In vivo tissue regeneration with robotic implants.

Science robotics·2020
Same author

Regenerative robotics.

Birth defects research·2019

Related Experiment Video

Updated: May 3, 2026

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2
09:33

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2

Published on: May 9, 2017

8.7K

Yeast-Driven and Bioimpedance-Sensitive Biohybrid Soft Robots.

MennaAllah Soliman1, Frederick Forbes1,2, Dana D Damian1,2,3

  • 1School of Electrical and Electronic Engineering, University of Sheffield, Sheffield S1 3JD, UK.

Cyborg and Bionic Systems (Washington, D.C.)
|April 28, 2025
PubMed
Summary

This study introduces biohybrid robots powered by yeast fermentation for adaptable robotic functions. Yeast

More Related Videos

Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

8.6K
Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators
14:42

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators

Published on: April 25, 2020

8.2K

Related Experiment Videos

Last Updated: May 3, 2026

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2
09:33

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2

Published on: May 9, 2017

8.7K
Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

8.6K
Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators
14:42

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators

Published on: April 25, 2020

8.2K

Area of Science:

  • Robotics
  • Biotechnology
  • Bioengineering

Background:

  • Biohybrid robots merge biological components with synthetic materials for novel robotic capabilities.
  • Yeast fermentation offers a unique biological process for generating actuation and sensing in soft robotic systems.

Purpose of the Study:

  • To leverage yeast fermentation dynamics for actuation and sensing in biohybrid soft robotic systems.
  • To integrate bioimpedance sensing for real-time monitoring of yeast behavior and metabolic activity.

Main Methods:

  • Utilized yeast fermentation to generate CO2 pressure for robotic actuation.
  • Developed an adjustable single-resistor oscillator circuit with a digital potentiometer for bioimpedance sensing.
  • Modeled yeast growth rate based on measured impedance frequency.

Main Results:

  • Demonstrated the feasibility of yeast-driven biohybrid robots with lifelike behavior.
  • The bioimpedance sensing circuit showed sensitivity to yeast concentration and correlated with actuation power.
  • Developed functional prototypes including a rotating soft limb, tactile sensor, palpation probe, and gripper.

Conclusions:

  • Yeast fermentation dynamics and bioimpedance sensing can significantly enhance biohybrid robotic functionality.
  • This research provides a foundation for developing advanced, adaptable biohybrid robotic systems.