Cobalt-Catalyzed Diester Formation with CO at Atmospheric Pressure via Three-Component Reactions

We propose a cobalt-catalyzed three-component reaction conducted under mild conditions. Following the carbonyl insertion at atmospheric pressure, the reaction proceeds via a nucleophilic attack by alcohols to form diesters. Notably, the scope of nucleophilic reagents can be extended to include a range of anilines. Furthermore, the products of this transformation serve as crucial synthetic building blocks for diverse organic synthesis processes, with subsequent derivatizations yielding promising results.