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A Plea for a Genetics-First Approach in Arrhythmogenic Cardiomyopathies

Anneline S J M Te Riele1, J Peter van Tintelen2, Richard N W Hauer1

  • 1Departments of Cardiology (A.S.J.M.t.R., R.N.W.H.), University Medical Center Utrecht, The Netherlands.

Circulation
|April 28, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Editorialsarrhythmiacardiomyopathydeath, suddendiagnosisgenegeneticsmanagement, clinical

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Mechanism of Cardiac Arrhythmias01:28

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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