Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photochemical Electrocyclic Reactions: Stereochemistry01:26

Photochemical Electrocyclic Reactions: Stereochemistry

1.8K
The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation
1.8K
Cycloaddition Reactions: MO Requirements for Photochemical Activation01:12

Cycloaddition Reactions: MO Requirements for Photochemical Activation

2.0K
Some cycloaddition reactions are activated by heat, while others are initiated by light. For example, a [2 + 2] cycloaddition between two ethylene molecules occurs only in the presence of light. It is photochemically allowed but thermally forbidden.
2.0K
Polymer Classification: Stereospecificity01:26

Polymer Classification: Stereospecificity

2.3K
Polymerization generates chiral centers along the entire backbone of a polymer chain. Accordingly, the stereochemistry of the substituent group has a significant effect on polymer properties. Polymers formed from monosubstituted alkene monomers feature chiral carbons at every alternate position in the polymer backbone. Relative to the predominant orientation of substituents at the adjacent chiral carbons, the polymer can exist in three different configurations: isotactic, syndiotactic, and...
2.3K
Thermal and Photochemical Electrocyclic Reactions: Overview01:26

Thermal and Photochemical Electrocyclic Reactions: Overview

2.2K
Electrocyclic reactions are reversible reactions. They involve an intramolecular cyclization or ring-opening of a conjugated polyene. Shown below are two examples of electrocyclic reactions. In the first reaction, the formation of the cyclic product is favored. In contrast, in the second reaction, ring-opening is favored due to the high ring strain associated with cyclobutene formation.
2.2K
Cycloaddition Reactions: MO Requirements for Thermal Activation01:16

Cycloaddition Reactions: MO Requirements for Thermal Activation

3.5K
Thermal cycloadditions are reactions where the source of activation energy needed to initiate the reaction is provided in the form of heat. A typical example of a thermally-allowed cycloaddition is the Diels–Alder reaction, which is a [4 + 2] cycloaddition. In contrast, a [2 + 2] cycloaddition is thermally forbidden.
3.5K
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

2.5K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photo-Induced Cracking in a Bi-Component Molecular Solid: Capturing Structural Intermediates.

Chemistry, an Asian journal·2025
Same author

Clues from an ionic cocrystal structure: from catalysis to mechanochemistry.

RSC advances·2024
Same author

Exploiting benzilic acid as a modular template: controlling photoreactivity and solid to liquid transition during photodimerization.

Chemical communications (Cambridge, England)·2023
Same author

Halogenated building blocks for 2D crystal engineering on solid surfaces: lessons from hydrogen bonding.

Chemical science·2019
Same author

Exploring the role of ionic liquids to tune the polymorphic outcome of organic compounds.

Chemical science·2018
Same author

Two-dimensional crystal engineering using halogen and hydrogen bonds: towards structural landscapes.

Chemical science·2017
Same journal

Assessing crystallisation behaviour in molecular crystals through particle rugosities.

Communications chemistry·2026
Same journal

Machine-learning-assisted continuous flow synthesis of clonidine.

Communications chemistry·2026
Same journal

A combined computational and experimental approach to revisit the Butlerov reaction.

Communications chemistry·2026
Same journal

Structure and mechanism of inhibition of lysine demethylase 2A (KDM2A) by compound 183c.

Communications chemistry·2026
Same journal

Recyclable glass fiber-reinforced epoxy copper clad laminates for printed circuit board.

Communications chemistry·2026
Same journal

Photolytic disruption of Alzheimer's amyloid Aβ<sub>42</sub>-fibrils by sialic-acid decorated glycodendrimers.

Communications chemistry·2026
See all related articles

Related Experiment Video

Updated: May 9, 2025

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
09:33

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch

Published on: February 7, 2022

3.3K

Regulating photoreactivity in a polymorphic bi-component solid through large synthons.

Mollah Rohan Ahsan1, Arijit Mukherjee2

  • 1Department of Chemistry, Birla Institute of Technology and Science, Pilani, Hyderabad Campus, Medchal District, Telangana, India.

Communications Chemistry
|April 30, 2025
PubMed
Summary
This summary is machine-generated.

Researchers engineered two distinct crystal polymorphs using Long-range Synthon Aufbau Modules (LSAM). These polymorphs exhibit unique photochemical and photomechanical properties, including isomerization and photodimerization, offering new avenues for material property engineering.

More Related Videos

Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization
12:19

Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization

Published on: November 29, 2018

8.4K
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

6.7K

Related Experiment Videos

Last Updated: May 9, 2025

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
09:33

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch

Published on: February 7, 2022

3.3K
Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization
12:19

Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization

Published on: November 29, 2018

8.4K
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

6.7K

Area of Science:

  • Materials Science
  • Crystallography
  • Photochemistry

Background:

  • Polymorphism in bi-component crystals is crucial for tailoring material properties.
  • Controlling crystal structure enables precise engineering of molecular solids.

Purpose of the Study:

  • To derive and characterize two distinct polymorphs of a functional bi-component molecular solid.
  • To investigate the photochemical and photomechanical behaviors of these polymorphs.

Main Methods:

  • Utilized Long-range Synthon Aufbau Modules (LSAM) for crystal engineering.
  • Tuned substituent nature and position to control polymorphism.
  • Analyzed photochemical reactions (cis-trans isomerization, [2+2] photodimerization) and photomechanical responses.

Main Results:

  • Successfully derived two polymorphs (Form I and Form II) with distinct structures.
  • Form I exhibited partial cis-trans isomerization upon photo-irradiation.
  • Form II underwent [2+2] photodimerization and a photo-induced solid-to-liquid transition.
  • Photomechanical responses varied with crystal morphology for Form I.

Conclusions:

  • Demonstrated the ability to engineer distinct crystal polymorphs with tunable photochemical and photomechanical properties.
  • Highlighted the potential of LSAM in designing functional molecular solids for advanced applications.
  • Showcased unique photo-responsive behaviors, including isomerization, photodimerization, and phase transitions.