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Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
Published on: February 1, 2017
The Japanese initiative for the Global Research Network and Link on Infectious Diseases (J-GRID+) Program and its
Miyako Otsuka1, Koji Wada1, Masaki Omori1
1National Center for Global Health and Medicine, Tokyo, Japan.
Abstract:
In response to the urgent need to strengthen Japan's capabilities in vaccine and pharmaceutical development for future infectious disease outbreaks, a global research "network" aimed at enhancing international collaboration was conceived. As a result, the Japanese initiative for the Global Research Network and Link on Infectious Diseases (J-GRID+), funded by the Japan Agency for Medical Research and Development (AMED), was launched in 2023. The aim of this article is to share our initiative to strengthen the global research network to prepare for infectious disease crises. Institutions participating in the J-GRID+ network have been conducting infectious disease research hubs under the previous "Japan Initiative for Global Research Network on Infectious Diseases (J-GRID project)" which supported over 20 years. The J-GRID+ was established for two key components: i) the "Overseas Research Centers Development", which strengthens research capacities in regions affected by infectious diseases through collaboration between Japanese universities and overseas research institutions, and ii) the "Operation of the J-GRID+ Network Core Center" to strengthen the monitoring of the information of signs of infectious disease outbreaks globally, to support each research center, and to strengthen communication as a global network. In April 2025, the newly established Japan Institute for Health Security (JIHS) will serve as the core center. With this outlook, J-GRID+ strives to be an enduring platform that supports global health security while respecting and strengthening international relationships.
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