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Related Experiment Video

Updated: May 9, 2025

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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A PARYLENE-BASED MEMS INTRAVASCULAR IMPLANT FOR WIRELESS CARDIAC PACING.

Kuang-Ming Shang1, Tzung Hsiai2, Yu-Chong Tai1

  • 1Department of Medical and Electrical Engineering, Caltech, Pasadena, CA, USA.

Proceedings. IEEE International Conference on Micro Electro Mechanical Systems
|May 5, 2025
PubMed
Summary
This summary is machine-generated.

We developed a miniaturized wireless cardiac pacemaker implantable via catheter. This device ensures reliable cardiac stimulation through innovative inductive power transfer, even with slight coil misalignment.

Keywords:
Cardiac StimulationInductive Power TransferMEMS Intravascular ImplantMicropacerPacemakerParylene PCBRoll-to-capsuleThermal forming

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Area of Science:

  • Biomedical Engineering
  • Medical Devices
  • Cardiovascular Technology

Background:

  • Traditional pacemakers require invasive surgical implantation and transvenous leads, posing risks of infection and lead dislodgement.
  • Existing wireless pacing systems often face challenges with power delivery consistency and miniaturization for intravascular deployment.

Purpose of the Study:

  • To develop and evaluate a novel Micro-Electro-Mechanical Systems (MEMS) intravascular implant for wireless cardiac pacing.
  • To engineer a compact, catheter-deliverable micropacer with a robust wireless power transfer system.

Main Methods:

  • Fabrication of a one-piece micropacer using a roll-to-capsule technique, incorporating a parylene circuit board, stimulating electrodes, and encapsulation.
  • Implementation of a low-frequency inductive power transfer system with back-to-back coil configuration for consistent energy delivery.
  • Benchtop testing to assess the device's electrical output and performance under varying coil separations.

Main Results:

  • The MEMS micropacer was successfully fabricated with a compact form factor (1.8 mm diameter, 12 mm length).
  • The device demonstrated consistent power delivery, achieving a 3.5V DC output voltage at a one-inch coil separation.
  • The catheter-delivered design facilitates minimally invasive insertion into the cardiac vein.

Conclusions:

  • The developed MEMS intravascular implant represents a significant advancement in wireless cardiac pacing technology.
  • The innovative design and power transfer system offer a promising solution for improved cardiac stimulation with reduced invasiveness.
  • Further in-vivo studies are warranted to validate the safety and efficacy of this novel cardiac pacing device.