Related Experiment Video
Updated: May 9, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Medicare Part D Preferred Pharmacy Networks And The Risk For Pharmacy Closure, 2014-23
Jenny S Guadamuz1, G Caleb Alexander2, Genevieve P Kanter3
1Jenny S. Guadamuz (jennyguadamuz@berkeley.edu), University of California Berkeley, Berkeley, California.
Medicare Part D plans create preferred pharmacy networks, often excluding independent and minority neighborhood pharmacies. These non-preferred pharmacies face a significantly higher risk of closure.
Area of Science:
- Health Services Research
- Pharmacy Management
- Health Equity
Background:
- Medicare Part D prescription drug plans utilize preferred pharmacy networks to control costs and guide beneficiaries.
- These networks can influence patient choice and pharmacy viability.
Purpose of the Study:
- To investigate disparities in preferred pharmacy network inclusion within Medicare Part D plans.
- To examine the association between preferred network status and pharmacy closure risk.
Main Methods:
- Analysis of Medicare Part D plan network data.
- Comparison of preferred vs. non-preferred pharmacy characteristics, including location and ownership.
- Statistical analysis of pharmacy closure rates based on network status.
Main Results:
- Independent pharmacies and those in low-income, Black, and Latinx neighborhoods were less likely to be included in preferred Part D networks.
- Pharmacies excluded from preferred networks exhibited a 70-350% increased likelihood of closure compared to preferred pharmacies.
Conclusions:
- Medicare Part D preferred networks may exacerbate health inequities by disproportionately disadvantaging pharmacies serving vulnerable populations.
- Policies addressing network design are needed to ensure equitable access to community pharmacies for all Medicare beneficiaries.
More Related Videos
Related Concept Videos
Nonlinear Pharmacokinetics: Overview
Nonlinearity can arise due to the saturation of plasma protein-binding or...
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Pharmacokinetic Models: Overview
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Nonlinear Pharmacokinetics: Causes of Nonlinearity
Nonlinear drug absorption can occur when the process is rate-limited by solubility, carrier-mediated transport systems, or saturation of the presystemic gut wall or hepatic metabolism. For instance, high doses of riboflavin...

