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Published on: December 4, 2021
Infected mesh salvaging using negative pressure wound therapy with instillation (NPWTi): a case report.
Nicolò Fabbri1, Riccardo Soverini1, Antonio Pesce1
1General Surgery Unit, Azienda Local Health Agency of Ferrara, Ferrara, Italy.
AME Case Reports
|May 7, 2025
Summary
Negative pressure wound therapy with instillation (NPWTi) may effectively treat abdominal wall mesh infections, potentially avoiding prosthesis removal in high-risk patients. This approach offers a promising option for complex wound healing.
Area of Science:
- Wound Healing
- Surgical Site Infections
- Biomaterials
Background:
- Abdominal wall wound dehiscence with mesh exposure is a severe complication with significant mortality.
- Standard protocols for negative pressure wound therapy with instillation (NPWTi) duration are lacking.
- Limited evidence exists for treating polypropylene mesh infections with NPWTi.
Observation:
- A 54-year-old patient with comorbidities developed wound dehiscence and mesh exposure post-hernia repair.
- NPWTi with sodium hypochlorite was used to treat the exposed mesh infection.
- The treatment led to normalized inflammatory markers and wound improvement without prosthesis removal.
Findings:
- NPWTi can be an effective treatment for infected mesh in abdominal wall dehiscence.
- This therapy may help salvage prosthetics in high-risk surgical patients.
- Successful NPWTi application was demonstrated in a complex case report.
Implications:
- NPWTi offers a potential alternative to mesh removal in specific cases of prosthetic infection.
- This case highlights the utility of NPWTi in managing challenging surgical site complications.
- Further research is warranted to establish optimal NPWTi protocols for mesh infections.
