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Neuromelioidosis in a child from Southern India: Diagnostic and therapeutic insights
Pratibha Bhat U1, Asem Ali Ashraf1, Anulekha Roy1
1Nitte (Deemed to be University), KS Hegde Medical Academy (KSHEMA), Department of Microbiology, Mangalore, Karnataka, India.
Abstract:
Melioidosis, caused by Burkholderia pseudomallei, presents with diverse clinical manifestations. This is a case of a 1-year-old female presenting with fever, and altered sensorium. Her MRI had revealed features suggestive of brainstem encephalitis. Cerebrospinal fluid analysis confirmed the presence of Burkholderia pseudomallei. Treatment involved a two-phase antibiotic therapy: the acute phase and the eradication phase, and after 14 days of appropriate antibiotics, the patient stabilized and was discharged with follow-up care. This case underscores the importance of recognizing the rare neurological presentation of neuromelioidosis in pediatric patients, emphasizing the need for timely diagnosis and treatment to improve outcomes.
Insights
Neuromelioidosis, a rare neurological condition caused by Burkholderia pseudomallei, can affect children. Early diagnosis and a two-phase antibiotic treatment are crucial for recovery, as shown in this pediatric case study.
Area of Science:
- Infectious Diseases
- Neurology
- Pediatrics
Background:
- Melioidosis, caused by Burkholderia pseudomallei, presents with varied clinical symptoms.
- Neurological involvement, or neuromelioidosis, is a rare but serious manifestation.
- Pediatric cases of neuromelioidosis require specific diagnostic and management considerations.
