Causal Overgeneralization of COVID-19 Vaccine Adverse Events Undermines Scientific Integrity: A Technical Report

Public discourse surrounding COVID-19 vaccines has often been marred by the overgeneralization of adverse events, where any health issue following vaccination is presumed to be vaccine-induced. This misattribution undermines pharmacovigilance efforts, making it harder to identify true safety signals, while fueling misinformation. Given the large-scale, global vaccination effort, coincidental health events are inevitable and must be distinguished from genuine adverse reactions using robust epidemiological and mechanistic assessments. This editorial highlights the importance of statistical rigor in vaccine safety evaluations, emphasizing the need for objective, evidence-based analysis to maintain scientific integrity and public trust.