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Updated: May 14, 2025
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
Published on: February 9, 2020
Evaluating lymphadenopathy
Clay W Walker1, Brittney Hulsey, Manuel Pompa
1Clay W. Walker is an assistant professor of family medicine at Mayo Clinic in Phoenix, Ariz., and an assistant professor in the Physician Assistant Studies Department at A.T. Still University in Mesa, Ariz. Brittney Hulsey is an associate professor in and director of the PA program at A.T. Still University. Manuel Pompa practices family medicine at Mayo Clinic. Clay W. Walker discloses receipt of consultancy fees from GlaxoSmithKline. The authors have disclosed no other potential conflicts of interest, financial or otherwise.
Abstract:
Lymphadenopathy (LAD), characterized by abnormal enlargement of lymph nodes, is frequently encountered in clinical practice. Despite its prevalence, the condition's evaluation and management pose significant challenges due to its diverse etiologies, which range from benign conditions to serious malignancies. This article provides a comprehensive overview of LAD, including its etiology, pathophysiology, clinical presentation, and diagnostic evaluation to aid providers, particularly physician associates (PAs), in care of these patients. Through detailed discussions and practical guidance, the article equips PAs with the necessary tools to effectively navigate the complexities of LAD.
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