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Macular Resurfacing With Autologous Internal Limiting Membrane Patch Transposition for Epiretinal Membrane
Xu Gao1,2, Mengxiao Wu1,2, Xuerui Zhang1,2
1Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; and.
Retina (Philadelphia, Pa.)
|May 13, 2025
Summary
A modified technique using a non-inverted autologous Inner Limiting Membrane (ILM) patch improved vision for patients with Epiretinal Membrane (ERM). Further studies are needed to confirm its effect on macular thickness.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Macular Diseases
Background:
- Epiretinal Membrane (ERM) affects vision by distorting the macula.
- Current treatments involve Inner Limiting Membrane (ILM) peeling, which can have limitations.
Purpose of the Study:
- To present a modified ILM peeling technique using autologous ILM patch transposition for ERM treatment.
- To evaluate the anatomical and functional outcomes of this novel surgical approach.
Main Methods:
- Retrospective case series of eight eyes with ERM undergoing vitrectomy.
- Utilized a non-inverted autologous ILM patch transposition technique.
- Assessed outcomes via optical coherence tomography and best-corrected visual acuities (BCVAs).
Main Results:
- Significant improvement in BCVA from 0.8 to 0.2 logMAR (P<0.001).
- No statistically significant reduction in central macular thickness (CMT).
- No ERM recurrence observed during an average follow-up of 8.3 months.
Conclusions:
- The non-inverted autologous ILM patch transposition is a feasible technique for ERM.
- Early postoperative visual acuity improvement is a potential benefit.
- Further investigation is required to determine the effect on CMT with larger studies.
