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Updated: Jun 14, 2026
18:50
Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
13.6K
Flow diversion for distal cerebral aneurysms: a systematic review and meta-analysis
Ahmet Günkan1, Marina Vilardo2, João Paulo Liute Scarramal3
1Radiologica, Unidade General Osório, Nova Friburgo, Rio de Janeiro, Brazil.
Journal of Neurointerventional Surgery
|May 13, 2025
Summary
Flow diverters (FDs) show promise for treating distal cerebral aneurysms (DCAs). This review found FDs to be safe and effective, with high occlusion rates and low complication risks.
Area of Science:
- Neuroendovascular surgery
- Cerebrovascular disease management
- Medical device technology
Background:
- Distal cerebral aneurysms (DCAs) are challenging to treat.
- Flow diverters (FDs) are increasingly used off-label for DCAs.
- Limited data exist on the safety and efficacy of FDs for DCAs.
Purpose of the Study:
- To synthesize current evidence on FD treatment for DCAs.
- To evaluate the safety and efficacy of FDs in treating DCAs.
- To provide a meta-analysis of FD treatment outcomes for DCAs.
Main Methods:
- Systematic review and meta-analysis of 18 studies.
- Included 441 patients and 445 DCAs.
- Analyzed efficacy (occlusion, retreatment) and safety (outcomes, complications).
Main Results:
- High adequate (90%) and complete (79%) occlusion rates.
- Low retreatment rate (1.6%) and good functional outcome (97%).
- Low procedure-related complications (9%), morbidity (1.5%), and mortality (0.6%).
Conclusions:
- Flow diverters are safe and effective for treating distal cerebral aneurysms.
- High occlusion rates and favorable safety profiles observed.
- Further research may support wider FD use in DCAs.
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