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Always Getting Lost: Defining Developmental Topographical Disorientation (DTD)-A Systematic Literature Review
Ineke J M van der Ham1, Michiel H G Claessen2
1Department of Health, Medical and Neuropsychology, Faculty of Social Sciences, Leiden University, Wassenaarseweg, 52, 2333, Leiden, AK, the Netherlands. c.j.m.van.der.ham@fsw.leidenuniv.nl.
Neuropsychology Review
|May 13, 2025
Summary
Developmental topographical disorientation (DTD) impairs navigation in healthy individuals, primarily due to poor mental map quality. Landmark knowledge is usually unaffected, guiding future assessment tool development.
Area of Science:
- Neuroscience
- Cognitive Psychology
- Spatial Cognition
Background:
- Developmental topographical disorientation (DTD) is a navigation impairment affecting daily life.
- A clear clinical definition and assessment tools for DTD are lacking.
- Recent theoretical frameworks allow for classifying navigation impairments.
Purpose of the Study:
- To clarify the behavioral characteristics of DTD by reviewing empirical evidence.
- To utilize recent theoretical developments in navigation impairment classification.
- To inform the development of a clinical definition and assessment tools for DTD.
Main Methods:
- Systematic literature review of empirical studies on DTD.
- Identification of DTD descriptions and criteria.
- Classification of DTD performance across navigation domains (landmark, location, path knowledge).
Main Results:
- DTD is characterized by impaired allocentric location and path knowledge, indicating poor mental map quality.
- Landmark knowledge is generally unaffected in DTD.
- Impaired landmark knowledge may suggest a broader visual agnosia.
Conclusions:
- Poor mental map quality is the primary characteristic of DTD.
- DTD navigation strategies appear landmark-focused.
- Findings support the development of a clinical characterization and assessment tools for DTD.

