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Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing™-Assisted Colonoscopy: A Randomized
Nabil Mohammad Azmi1, Prem Kumar Gopal1, Muhammad Irfan Abdul Jalal2
1Department of Surgery, Faculty of Medicine, The National University of Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Diagnostics (Basel, Switzerland)
|May 14, 2025
Summary
Endo-Wing™-assisted colonoscopy significantly increases adenoma detection rates (ADR) compared to standard colonoscopy. This device improves visualization by flattening folds, leading to better detection of colorectal adenomas.
Area of Science:
- Gastroenterology
- Endoscopy
- Medical Devices
Background:
- Colorectal cancer (CRC) screening relies on colonoscopy to detect adenomas.
- Improving adenoma detection rate (ADR) is crucial for effective CRC prevention.
- Standard colonoscopy visualization can be limited by colonic folds.
Purpose of the Study:
- To compare the adenoma detection rate (ADR) between standard colonoscopy and colonoscopy utilizing the Endo-Wing™ device.
- To evaluate the efficacy of Endo-Wing™ in enhancing visualization during colonoscopy.
Main Methods:
- A single-center, randomized controlled trial involving 192 participants (aged 45+) at risk for colorectal cancer.
- Participants were randomized 1:1 to undergo either standard colonoscopy or Endo-Wing™-assisted colonoscopy.
- The primary endpoint was the adenoma detection rate (ADR).
Main Results:
- Endo-Wing™-assisted colonoscopy demonstrated a significantly higher ADR compared to standard colonoscopy (p=0.005).
- The number and size of detected adenomas were also significantly greater in the Endo-Wing™ group.
- Cecal intubation rates and sedation requirements were comparable between the groups, with no reported adverse events.
Conclusions:
- Endo-Wing™-assisted colonoscopy is effective in improving ADR.
- The device enhances visualization, leading to increased detection of colorectal adenomas.
- Endo-Wing™ represents a promising advancement for colonoscopy procedures.
