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Updated: Jun 13, 2025
Isolation and Characterization of Microvesicles from Peripheral Blood
Published on: January 6, 2017
Multi-line lateral flow immunoassay for the detection and subtyping of breast cancer-derived small extracellular
Chloe Duffield1, Laura M Rey Gomez1, Su Su Thae Hnit1
1School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Australia. yuling.wang@mq.edu.au.
Abstract:
Cancer cell-derived small extracellular vesicles (sEVs) are new promising biomarkers for improved cancer diagnosis. A multi-line lateral flow immunoassay (LFIA) has been proposed for sensitive detection and subtyping of breast cancer-derived sEVs. The expression of cancer surface biomarkers (EpCAM) was confirmed through colorimetric analysis of cell line-derived sEVs (p = 0.076) and patient samples, highlighting the potential for their use as a clinical aid.
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