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Updated: May 23, 2025
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Mixed Reality Assisted Radical Endoscopic Thyroidectomy
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Management of Adverse Events During Treatment for Advanced Thyroid Cancer
Thomas J Roberts1,2, Lori J Wirth1,2
1Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Summary
Managing treatment-related adverse events (TRAEs) is key for advanced thyroid cancer patients on new therapies. This review details common TRAEs and effective strategies to improve patient quality of life and outcomes.
Area of Science:
- Oncology
- Pharmacology
- Clinical Medicine
Background:
- Advanced thyroid cancer treatment has improved with multikinase and gene-specific inhibitors.
- Managing treatment-related adverse events (TRAEs) is crucial for patient quality of life and treatment success.
Purpose of the Study:
- To review common and significant TRAEs associated with advanced thyroid cancer treatments.
- To summarize effective management strategies for these TRAEs.
Main Methods:
- A narrative review of published literature was conducted.
- Information on TRAE incidence and management approaches was synthesized.
Main Results:
- Common TRAEs include fatigue, hypertension, gastrointestinal toxicities, rashes, and hand-foot syndrome.
- Significant TRAEs like pyrexia syndrome, thromboembolic events, and cardiac impairment require specific attention.
Conclusions:
- Evidence-based management approaches exist for many common TRAEs in advanced thyroid cancer.
- Optimizing TRAE management improves patient outcomes and quality of life.
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