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Factors associated with constipation in infants from six to 12 months of age: a case-control study

Alma Rocío Cisneros-Abundis1, Andrea Anaís García-Contreras1, Edgar M Vásquez-Garibay2

  • 1Centro Universitario de Ciencias de la Salud, Instituto de Nutrición Humana. Universidad de Guadalajara, México.

Revista Espanola De Enfermedades Digestivas
|May 26, 2025
PubMed

Insights

Functional constipation in infants (6-12 months) involves changes in bowel habits without physical abnormalities. Identifying associated factors is crucial for understanding these brain-gut axis disorders.

Area of Science:

  • Pediatric Gastroenterology
  • Neurogastroenterology
  • Developmental Pediatrics

Background:

  • Brain-gut axis disorders (BIGDs) present with recurrent GI symptoms but lack structural or inflammatory causes.
  • Infants aged 6-12 months often exhibit altered defecatory patterns, including reduced bowel movement frequency and increased stool consistency.

Purpose of the Study:

  • To investigate and identify factors associated with functional constipation in infants aged 6-12 months.
  • To enhance understanding of early-life brain-gut interactions in pediatric functional disorders.

Main Methods:

  • This study focuses on observational data collection in infants aged 6-12 months.
  • Analysis involves correlating defecatory pattern changes with potential contributing factors.

Main Results:

  • Functional constipation in infants is characterized by decreased bowel movement frequency and harder stools.
  • Specific contributing factors for functional constipation in this age group remain largely unidentified.

Conclusions:

  • Early identification of factors influencing infant functional constipation is essential for targeted interventions.
  • Further research is needed to elucidate the etiology of brain-gut axis disorders in early childhood.

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