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PDE4 Inhibitors: Bridging Molecular Insights With Clinical Impact

Naiem T Issa, Sabine Obagi, Giovanni Damiani

    Journal of Drugs in Dermatology : JDD
    |June 4, 2025
    PubMed
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    Phosphodiesterase-4 (PDE4) inhibitors offer non-steroidal treatment for inflammatory skin diseases. Roflumilast demonstrates superior potency and selectivity, leading to improved patient outcomes and tolerability in topical formulations.

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