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Cone-beam CT (CBCT) images from Gamma Knife ICON can be used for accurate dose calculations. Using a specific three-level electron density curve with CBCT data ensures good agreement with CT-based calculations.

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Area of Science:

  • Medical Physics
  • Radiotherapy
  • Imaging Technology

Background:

  • Accurate dose calculation is crucial for effective radiotherapy.
  • Cone-beam computed tomography (CBCT) offers in-room imaging capabilities.
  • Assessing CBCT suitability for dose calculation is essential for treatment planning.

Purpose of the Study:

  • To evaluate the accuracy of dose calculations using CBCT images with the convolution algorithm.
  • To compare dose calculations derived from CBCT with those from conventional CT images.

Main Methods:

  • Developed a CT to electron density curve for the Gamma Knife ICON CBCT scanner.
  • Created a three-level stepwise electron density curve for specific tissues.
  • Calculated beam on times for 10 patients using CT, CBCT (two methods), and TMR10 algorithms.

Main Results:

  • Ratios of beam on times (convolution vs. TMR10) varied depending on the imaging method.
  • CBCT with a Hounsfield unit electron density curve showed a ratio of 1.216.
  • CBCT with a three-level stepwise curve showed a ratio of 1.052, indicating good agreement.

Conclusions:

  • CBCT images alone may underestimate dose compared to CT-based convolution.
  • Employing CBCT with a fixed three-level electron density curve provides dose calculation agreement comparable to CT-based methods.
  • This approach enhances the utility of CBCT in radiotherapy dose calculations.