Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reirradiation treatment effects in the clinic (ReTEC) proposal - proof of concept based on spinal cord dose tolerance for reirradiation with stereotactic body radiotherapy.

Journal of applied clinical medical physics·2026
Same author

Correction: Whole-Body Dose of Patients Treated With ZAP-X Intracranial Gyroscopic Stereotactic Radiosurgery.

Cureus·2026
Same author

Palliative External Beam Radiation Therapy for Dysphagia in a 101-Year-Old Man With Esophageal Adenocarcinoma.

Cureus·2026
Same author

Localized Nonablative Neuromodulatory Irradiation of the Nucleus Accumbens Ameliorates Voluntary Excessive Alcohol Consumption in Miniature Pigs.

Neuromodulation : journal of the International Neuromodulation Society·2025
Same author

Erratum: Global Growth and Distribution of CyberKnife Stereotactic Radiosurgery: A Bibliometric Analysis: Corrigendum.

Neurosurgery practice·2025
Same author

Whole-Body Dose of Patients Treated With ZAP-X Intracranial Gyroscopic Stereotactic Radiosurgery.

Cureus·2025
Same journal

Upright radiation therapy systems: Requirements, performance and benefits.

Journal of radiosurgery and SBRT·2026
Same journal

Tomotherapy-based stereotactic radiosurgery and stereotactic body radiation therapy.

Journal of radiosurgery and SBRT·2026
Same journal

Spatially fractionated radiation therapy: A powerful and low-toxicity technique for cancer treatment.

Journal of radiosurgery and SBRT·2026
Same journal

CyberKnife stereotactic radiosurgery, stereotactic radiation therapy and stereotactic body radiation therapy: Technical and clinical updates.

Journal of radiosurgery and SBRT·2026
Same journal

Special issue on <i>Contemporary and emerging stereotactic radiosurgery and stereotactic body radiation therapy technology</i>.

Journal of radiosurgery and SBRT·2026
Same journal

Proton-based stereotactic radiosurgery and stereotactic body radiation therapy.

Journal of radiosurgery and SBRT·2026
See all related articles

Related Experiment Video

Updated: Apr 21, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.3K

Dedicated self-shielded Linac-based intracranial radiosurgery device: The ZAP-X.

Georg A Weidlich1, Alex E Maslowski1, John R Adler1

  • 1Zap Surgical Systems, Inc., 590 Taylor Way, San Carlos, CA 94070, USA.

Journal of Radiosurgery and SBRT
|April 20, 2026
PubMed
Summary
This summary is machine-generated.

The ZAP-X, a novel radiosurgery device, uses a linear accelerator, eliminating the need for cobalt sources and radiation bunkers. This innovation enables precise, faster treatments for brain, head, and neck conditions.

Keywords:
dedicated intracranial radiosurgerygyroscopicself-shieldedstereotactic radiosurgery

More Related Videos

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

15.3K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.9K

Related Experiment Videos

Last Updated: Apr 21, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.3K
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

15.3K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.9K

Area of Science:

  • Medical Physics
  • Neurosurgery
  • Radiation Oncology

Background:

  • The ZAP-X is a next-generation radiosurgery device utilizing a 3.0 MV S-band linear accelerator.
  • It replaces traditional 60Co sources, offering advanced capabilities for head and neck treatments.

Purpose of the Study:

  • To characterize the ZAP-X system from physics and application perspectives.
  • To highlight its advantages in precision, speed, and cost-effectiveness for radiosurgery.

Main Methods:

  • Description of the ZAP-X system, including its linear accelerator and robotic platform.
  • Analysis of its integrated radiation-shielding and gyroscopic mechanical structure.
  • Evaluation of its suitability for various intracranial and cervical lesions, including functional brain disorders.

Main Results:

  • The ZAP-X obviates the need for 60Co sources and radiation bunkers, reducing site preparation time and cost.
  • Its design enables precise, conformal, and faster radiosurgery delivery.
  • The steep dose gradient is advantageous for treating functional brain disorders.

Conclusions:

  • The ZAP-X represents a significant advancement in radiosurgery technology.
  • It offers a more accessible, efficient, and precise treatment option for a range of neurological and oncological conditions.
  • Its design facilitates broader adoption of advanced radiosurgery techniques.