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Transient restrictive cardiomyopathy in cats: first reported case series
Camille Poissonnier1,2,3, Pierre Guigo2, Pierre Foulex2,3
1Université Paris-Est, École Nationale Vétérinaire d'Alfort, ChuvAc, Maisons-Alfort, France.
Frontiers in Veterinary Science
|June 9, 2025
Summary
Transient restrictive cardiomyopathy (TRCM) in cats is a reversible condition often preceded by an event, with most cats experiencing excellent long-term prognoses. This study describes its features and outcomes.
Area of Science:
- Veterinary Cardiology
- Cardiovascular Physiology
- Feline Medicine
Background:
- Transient myocardial thickening, characterized by reversible left ventricular hypertrophy, left atrial dilation, and congestive heart failure, has been observed in cats.
- Transient restrictive cardiomyopathy (TRCM) has not been previously reported in feline medicine.
Purpose of the Study:
- To delineate the epidemiological, clinical, echocardiographic, and prognostic characteristics of cats diagnosed with TRCM.
- To differentiate TRCM from non-transient restrictive cardiomyopathy (NT-RCM) in cats.
Main Methods:
- A retrospective study involving 17 cats with TRCM and 16 control cats with NT-RCM.
- Cats were identified from veterinary databases based on an RCM phenotype (normal LV dimensions with atrial enlargement).
- TRCM cats exhibited resolution of the RCM phenotype, while NT-RCM cats had persistent findings.
Main Results:
- TRCM cats were significantly younger than NT-RCM cats.
- An antecedent event preceded diagnosis in most TRCM cats (11/17), unlike NT-RCM cats.
- TRCM cats showed a favorable prognosis, with an estimated 86% survival rate at 6,000 days, compared to NT-RCM cats.
Conclusions:
- Transient restrictive cardiomyopathy in cats is associated with antecedent events.
- TRCM in cats generally carries an excellent long-term prognosis.
- Early identification and management of TRCM can lead to positive outcomes in feline patients.
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